For full functionality of SBS 2008 (SBS2008) Remote Web Workplace, forward the following ports at your router or firewall:
SMTP 25 - Simple Mail Transfer Protocol
HTTP 80 - Home Page Web
SSL 443 - Home Page Web Secured HTTPS (RWW, OWA, remote desktop or Terminal Server sessions)
HTTP2 987 - Second SSL Secured on alternate port for SharePoint (optional)
PPTP 1723 - VPN Connections
Note: On SBS 2003, RWW used port 4125. This is now replaced by the Terminal Services Gateway which uses port 443 over HTTPS. The new setup works better for remote locations that have proxy servers which only allow certain types of traffic. HTTPS is so common that it is always an allowed traffic type
In addition, rather than opening port 25 for your Exchange incoming SMTP email